CareersJoin the Depixus team

Depixus is operating in one of the most dynamic and exciting areas of bioscience today. We are seeking highly talented individuals to join our teams based in both Paris, France and Cambridge, UK.

Technical excellence is very important but you will also need to be innovative, enterprising, and enjoy working within a close-knit team. The development of our technology requires scientists and engineers from a wide range of disciplines.

We accept resumes at all times; if you think you could help us then we would love to hear from you! For more information please contact: jobs@depixus.com. Positions that are currently open are listed below.

Current Vacancies

Depixus is a young and dynamic biotechnology company based in Paris. Our goal is to commercialize a highly innovative technology platform for the fast, accurate, and inexpensive extraction of genetic and epigenetic information from single molecules of DNA and RNA. Originally developed in the Physics Department of École Normale Supérieure (ENS) in Paris, the potential of this exciting technology has been recognized through the award of numerous grants and prizes for innovation at both national and international levels. You can read more about Depixus on our website (www.depixus.com).

Depixus currently has an open position for a full-time chemist, surface chemist, or materials scientist to work from our Paris offices/labs on various projects related to the development of our technology platform. This is a rare opportunity to play an important role in the development of a cutting-edge technology, and as part of a dynamic early-stage company.

 

Job Description

We are seeking an exceptional individual who enjoys working in a highly collaborative and fast paced R&D environment to join our multidisciplinary team. He/she will work with biologists, engineers, physicists and software engineers, both within Depixus and as part of collaborations with academic and OEM partners. The scientist in this position will play a critical role in the commercialization of our innovative and new technology platform for fingerprinting, sequencing, and epigenetic analysis of DNA and RNA. Therefore, demonstrated success in industrial and/or biotechnology product development is highly desired.

We seek a motivated scientist with experience in the chemical modification of surfaces and/or nanomaterials with small molecules, DNA, and/or biomolecules using primarily solution-phase methods. The candidate should be familiar with surface/nanomaterial characterization techniques (e.g., RAMAN, FTIR, DLS, XPS, SEM, AFM).  Experience with microfluidic and MEMS devices for bio-assays is preferred. Knowledge of click chemistries or noncovalent interaction chemistries (e.g., biotin/streptavidin, modification of double-stranded DNA) is desirable. Experience with plasma modification/deposition of surfaces, adhesion/bonding of surfaces, is a plus.  The candidate should also have demonstrated competence working both individually and in project teams.

 

Minimum Qualifications & Experience

  • Degree in chemistry, materials science, physics, or a closely-related field
  • Ph.D. or master’s with at least 3-5 years of industrial work experience in an R&D setting.
  • Strong background in surface chemistry and surface treatment through material design, synthesis, and characterization
  • Good communication skills in oral English. In particular, candidates should be capable of presenting technical information and data to non-experts in a clear and concise manner

 

Desirable Qualifications & Experience

  • A sound understanding of biochemistry, enzymology and commercial assay development
  • Experience in electrochemistry, plating and thin film coatings
  • Experience with microarrays or other chip-based nucleic acid analysis systems
  • Experience in nano-imprinting & nano-replication techniques
  • Experience in microfabrication, instrumentation, mechanical and electrical engineering, would all be beneficial.

Responsibilities

  • Work independently and with small teams to design, develop and execute experimental plans
  • Apply fundamental understanding of surface chemistry and molecular biology to the design, synthesis and evaluation of surface treatments using existing or novel methodologies
  • Interact closely with engineers and biologists to develop comprehensive solutions for microchip-based DNA analysis devices
  • Optimize existing methods, improve existing processes and develop scaling-up methods to achieve performance specifications required for commercialization
  • Participate in intellectual property creation and publications
  • Participate in group meetings and present work to group members

Location

  • The job will be based in Paris, France, with frequent travel to Cambridge, U.K.

 

Application procedure

Please send a current C.V. and cover letter via email to Depixus’s Chief Technology Officer, Chas Andre, at: chas.andre@depixus.com

Depixus is a young and dynamic biotechnology company based in both Paris, France and Cambridge, UK. Our aim is to commercialize a highly innovative technology platform for the fast, accurate, and inexpensive extraction of genetic and epigenetic information from single molecules of DNA and RNA. Originally developed in the Physics Department of École Normale Supérieure (ENS) in Paris, the potential of this exciting technology has been recognized through the award of numerous grants and prizes for innovation at both national and international levels. You can read more about Depixus on our website (www.depixus.com).

Depixus currently has an open position for a full-time Electronic Design Engineer to work on various projects related to the development of our technology platform. This is a rare opportunity to play an important role in the development of a cutting-edge technology, and as part of a dynamic early-stage company.

 

Job Description

We are seeking an exceptional individual who enjoys working in a highly collaborative and fast paced R&D environment to join our multidisciplinary team. The successful candidate will work with biologists, engineers, physicists and software engineers, both within Depixus and as part of collaborations with academic and OEM partners. He/she will play an important role in the commercialisation of our innovative new technology platform for the identification, sequencing, and epigenetic analysis of DNA and RNA.

The successful candidate will be part of Depixus’ engineering team and will be based primarily in Harston, Cambridgeshire, UK. He/she will work on various aspects of several ongoing instrumentation projects, with a focus on development of PCB-level electronics and customised mixed-signal integrated circuits (ICs). He/she will be a key contributor to the architecture-design, verification, layout, and testing of advanced mixed-signal circuits within customised IC and high-speed PCBs. A background in IC design (in particular, IC architecture-design) will therefore be vital.

More generally, the successful candidate will contribute to the overall development of the company’s technology platform. This will include the development of various interfaces to link function-control, mechanical, and microfluidic modules together. Close engagement with external partners will be important. Similarly, close collaboration with other Depixus teams will also be critical to ensure that any instrumentation developed is compatible with other requirements of the technology (e.g. biological sample preparation, surface chemistries, and down-stream data processing).

Overall, this role would suit candidates that have a solid background in the electronic aspects of design of scientific/biotechnology instrumentation (both at PCB and IC levels). Previous experience in the development of instrumentation/medical devices for genetic analysis would be of great value.

 

Required Qualifications, Experience, and Qualities

  • Masters-level degree in the field of mathematics, physics, electronic or biomedical engineering
  • Experience in the design of mixed-signal circuits, at the level of both PCBs and monolithic ICs
  • Knowledge of at least one PCB design software package (e.g., Orcad, Eagle, Altium, EasyPC)
  • Fully competent in the use of IC design software (e.g. Cadence)
  • Experience in working with at least one high-level programming language (e.g., C, VB, Java)
  • Ability to gather high-level requirements from stakeholders and, from these, to create appropriate IC architectures and specifications
  • Ability to translate written specifications into robust designs
  • Demonstrated ability to deliver high-quality solutions to difficult challenges
  • Demonstrated willingness to take ownership of individual and team tasks
  • Excellent interpersonal and communications skills
  • Both a team-player and able to work autonomously
  • Highly motivated and results-driven

 

Desirable Qualifications & Experience

  • Good understanding of design techniques in deep sub-micron CMOS processes (e.g. 0.13μm and below)
  • Experience in high-speed IC design
  • Experience in CMOS Electrochemical Impedance Spectroscopy (EIS) biosensor array design
  • Knowledge of Matlab with experience in digital filter design highly desirable
  • Experience with microcontroller programming
  • Experience with FPGA development tools, working with VHDL/Verilog
  • Knowledge of standard tests for EMI/EMC compliance and ESD
  • Team and/or project management experience
  • General familiarity with life sciences is advantageous but not required

 

Responsibilities

  • Supporting the development of Depixus’ innovative SIMDEQ instrument platform for combined genetic and epigenetic analysis.
  • Specifically:
    • Development of IC and PCB architectures
    • Component development, microfabrication, and integration
    • Engagement with suppliers to ensure high-quality and timely product delivery
    • Integration of instrumentation development with other projects within Depixus (e.g. molecular biology, surface chemistry, and data science)
  • Contribution to internal and external, informal and formal design reviews
  • Participation in group meetings, and presentation of work to group members

 

Location

  • The job will be based primarily in Depixus’ offices/labs in Harston, Cambridge, U.K. but will also involve frequent travel to the company’s offices/labs in Paris,

 

Application procedure

Please send a current C.V. and cover letter via email to Depixus’ Chief Technology Officer, Chas Andre, at: chas.andre@depixus.com