CareersJoin the Depixus® team

Depixus® is operating in one of the most dynamic and exciting areas of bioscience today. We are seeking highly talented individuals to join our teams based in both Paris, France and Cambridge, UK.

Technical excellence is very important but you will also need to be innovative, enterprising, and enjoy working within a close-knit team. The development of our technology requires scientists and engineers from a wide range of disciplines.

We accept resumes at all times; if you think you could help us then we would love to hear from you! For more information please contact: jobs@depixus.com. Positions that are currently open are listed below.

Current Vacancies in Paris (FR)

Depixus is a young and dynamic biotechnology company based in both Paris, France and Cambridge, UK. Our aim is to commercialize a highly innovative technology platform for the fast, accurate, and inexpensive extraction of genetic and epigenetic information from single molecules of DNA and RNA. Originally developed in the Physics Department of École Normale Supérieure (ENS) in Paris, the potential of this exciting technology has been recognized through the award of numerous grants and prizes for innovation at both national and international levels. You can read more about Depixus on our website (www.depixus.com).

Depixus currently has an open position for a full-time opto-mechanical/instrumentation assembly technician to work on various projects related to the development and production of our technology platform. This is a rare opportunity to play an important role in the development of a cutting-edge technology, and as part of a dynamic early-stage company.

 

Job Description

We are seeking an exceptional individual who enjoys working in a highly collaborative and fast paced R&D environment to join our multidisciplinary team. The successful candidate will work with biologists, engineers, physicists, and software engineers, both within Depixus and as part of collaborations with academic and OEM partners. He/she will play an important role in the commercialization of our innovative new technology platform for the identification, sequencing, and epigenetic analysis of DNA and RNA.

The successful candidate will be part of Depixus’ fast-growing engineering team and will be based in Paris, France. He/she will be mainly working on the assembly of various instruments and prototypes including optical, electronic, mechanical and fluidic subcomponents. Under the supervision of the Project Lead, he/she will play a key role in the production of our instruments, including assembly, calibration, quality control and reporting. He/she will work in close collaboration with the other team members to ensure that these instruments are of scientific-grade, and meet high overall product performance and stability specifications.

More generally, the successful candidate will contribute to the overall development of the company’s technology. This will include the development and testing of various hardware modules in the control system within our instrument systems. Close collaboration with other Depixus teams will also be critical to ensure that instrumentation hardware will be compatible with other aspects of the technology (e.g. biological sample preparation, surface chemistries, software, cartridge design, etc.).

Overall, this role would suit candidates with a solid background in the assembly and testing of scientific instruments, ideally for use in biomedical applications.  Previous experience in the development of instrument systems specifically for genetic analysis would be of great value.


Required Qualifications, Experience, and Qualities

 

  • Associate or bachelor’s degree or equivalent in optic, opto-mechanic, or instrumentation engineering
  • Industry-level experience of the different stages of instrument design and development
  • Rigorous attention to detail
  • Excellent interpersonal and communications skills
  • Both a team-player and able to work autonomously
  • Highly motivated and results-driven
  • A good command of spoken and written English

 

Desirable Qualifications & Experience

 

  • Previous experience in microscopy or complex optomechanical systems
  • Experience in genetic analysis or biotechnology instrument development would be a big plus, but is not essential

 

Responsibilities

 

  • Supporting the development of Depixus’ innovative instrument platform for combined genetic and epigenetic analysis.
  • Specifically:
    • Mechanical & high precision opto-mechanical assembly
    • Hardware integration
    • Instrument calibration
    • QC & compliance testing and reporting
    • Support of instrument deployment
  • Contribution to internal and external, informal and formal design reviews
  • Participation in group meetings, and presentation of work to group members

 

Location

 

  • The job will be based primarily in Depixus’ offices/labs in Paris, France, with the possibility of occasional travel to the company’s offices/labs in Cambridge U.K.

 

Application procedure

 

Please send a current C.V. and cover letter via email to Depixus’ Chief Technology Officer, Chas Andre, chas.andre@depixus.com

Depixus is a young and fast-growing biotechnology company based in both Paris, France and Cambridge, UK. Our aim is to commercialize a highly innovative technology platform for the fast, accurate, and inexpensive extraction of genetic and epigenetic information from single molecules of DNA and RNA. Originally developed in the Physics Department of École Normale Supérieure (ENS) in Paris, the potential of this exciting technology has been recognized through the award of numerous grants and prizes for innovation at both national and international levels. You can read more about Depixus on our website (www.depixus.com).

Depixus currently has an open position for a full-time Mechanical Engineer to work on various projects related to the development of our technology platform. This is a rare opportunity to play an important role in the development of a cutting-edge technology, and as part of a dynamic early-stage company.

 

Job Description

We are seeking an exceptional individual who enjoys working in a highly collaborative and fast paced R&D environment to join our multidisciplinary team. The successful candidate will work with biologists, engineers, physicists, and software engineers, both within Depixus and as part of collaborations with academic and OEM partners. He/she will play an important role in the commercialization of our innovative new technology platform for the identification, sequencing, and epigenetic analysis of DNA and RNA.

The successful candidate will be part of Depixus’ fast-growing engineering team and will be based primarily in Paris, France. He/she will work in close collaboration with the other team members to produce a scientific-grade instrument, with high overall product performance and stability requirements. More specifically, he/she will:

  • develop the mechanical layout of the optical components of Depixus’ instrument systems
  • produce CADs of the complete instrument system and cartridge elements
  • prototype and industrialize key opto-mechanical sub-elements of the instrument
  • plan and perform instrument validation and verification testing

Close engagement with external partners will be important. Similarly, close collaboration with other Depixus teams will also be critical to ensure that the hardware platform is compatible with other requirements of the technology (e.g. biological sample preparation, surface chemistries, software, cartridge design, etc.).

Overall, this role would suit candidates with a solid background in the development of scientific instruments for biomedical applications (ideally genetic analysis).

 

Required Qualifications, Experience, and Qualities

 

  • Masters-level or PhD level qualification in the field of mechanical or opto-mechanic engineering
  • Excellent skills in CAD design tools (ideally SolidWorks)
  • Industry experience of the design and development of scientific instrumentation
  • Demonstrated ability to deliver high-quality solutions to difficult challenges
  • Demonstrated willingness to take ownership of individual and team tasks
  • Excellent interpersonal and communications skills
  • Both a team-player and able to work autonomously
  • Highly motivated and results-driven
  • A good command of spoken and written English

 

Desirable Qualifications & Experience

 

  • Previous experience in microscopy or complex optomechanical systems
  • Experience in genetic sequencing or other biotechnology instrument development is a big plus but not essential
  • Previous experience with flexure systems and/or microfluidic cartridge modules would be useful
  • Knowledge of high precision mechanical machining tools
  • Familiarity with thermal control of instruments

 

Responsibilities

 

  • The successful candidate will:
    • develop the mechanical layout of the optical components of Depixus’ instrument systems
    • produce CADs of the complete instrument system and cartridge elements
    • prototype and industrialize key opto-mechanical sub-elements of the instrument
    • plan and perform instrument validation and verification testing
  • Contribute to internal and external, informal and formal design reviews
  • Participate in group meetings, and presentation of work to group members
  • Support and advise on other engineering matters related to development of Depixus’ innovative instrument systems.

 

Location

 

  • The job will be based primarily in Depixus’ offices/labs in Paris, France, with the possibility of occasional travel to the company’s offices/labs in Cambridge U.K.

 

Application procedure

Please send a current C.V. and cover letter via email to Depixus’ Chief Technology Officer, Chas Andre, at: chas.andre@depixus.com

Current Vacancies in Cambridge (UK)

Depixus is a young and dynamic biotechnology company based in both Paris, France and Cambridge, UK. Our aim is to commercialize a highly innovative technology platform for the fast, accurate, and inexpensive extraction of genetic and epigenetic information from single molecules of DNA and RNA. Originally developed in the Physics Department of École Normale Supérieure (ENS) in Paris, the potential of this exciting technology has been recognized through the award of numerous grants and prizes for innovation at both national and international levels. You can read more about Depixus on our website (www.depixus.com).

Depixus currently has an open position for a full-time Hardware Design Engineer to work on various projects related to the development of our technology platform. This is a rare opportunity to play an important role in the development of a cutting-edge technology, and as part of a dynamic early-stage company.

 

Job Description

We are seeking an exceptional individual who enjoys working in a highly collaborative and fast paced R&D environment to join our multidisciplinary team. The successful candidate will work with biologists, engineers, physicists and software engineers, both within Depixus and as part of collaborations with academic and OEM partners. They will play an important role in the commercialization of our innovative new technology platform for the identification, sequencing, and epigenetic analysis of DNA and RNA.

The successful candidate will be part of Depixus’ engineering team and will be based primarily in Harston, Cambridgeshire, UK. They will:

  • Work on several system engineering, electronics and ASIC design challenges in our current and future instrument platforms.
  • Lead all aspects of the design and verification of Depixus’ electronic hardware platform. This will include the levels from ASICs with multi-million transistors, to the system engineering with FPGAs running at its core through the PCIe interface.
  • Be a key contributor to the verification testing of Depixus’ advanced mixed-signal integrated circuits used for genetic analysis, including block-level and chip-level functional test plan development, test bench definition and simulation.
  • Assume responsibility for improving the design procedures/process flows that are associated with the hardware development.
  • Leverage their system-level integration experience, working with other members in the engineering team to deliver a high-performance solution.
  • Engage in development and commercialisation of instruments for volume production under relevant regulatory safety standards and directories. Therefore, familiarity with CE marking, FDA approval process and QMS in medical device is beneficial.

More generally, the successful candidate will contribute to the overall development of the company’s technology platform. This will include the development and test of various hardware modules in the control system within the instrument platform. Close engagement with external partners will be important. Similarly, close collaboration with other Depixus teams will also be critical to ensure that the hardware platform is compatible with other requirements of the technology (e.g. microchip fabrication, biological sample preparation, surface chemistries, software, cartridge and instrument design).

Overall, this role would suit candidates that have a solid background in FPGA development and hardware design and integration, particularly in biomedical applications.  Previous experience in the development of ASICs and FPGAs for genetic analysis would be of great value.

 

Required Qualifications, Experience, and Qualities

  • Masters-level degree in the field of computer science, electronic engineering or any other field that is pertinent to the industry
  • Experienced in operating the latest simulation and modelling equipment and design tools for all stages of FPGA design and development lifecycle
  • Experienced in using typical FPGA improvement platforms such as Actel Xilinx, Altera, etc.
  • Knowledgeable about high speed DSP and I/O in instrument control applications which require multi-gigabyte per second data transfer and signal processing
  • Experienced in designing high speed PCB/hardware to interface with FPGAs and ASICs.
  • Highly proficient in Verilog or VHDL
  • Experience with importing data processing algorithms to FPGAs that are developed using other high-level language, such as python.
  • Demonstrated ability to deliver high-quality solutions to difficult challenges
  • Demonstrated willingness to take ownership of individual and team tasks
  • Excellent interpersonal and communications skills
  • Both a team-player and able to work autonomously
  • Highly motivated and results-driven

 

Desirable Qualifications & Experience

  • Experience in domain expertise in standard bus, memory, networking protocols, such as PCIe, SPI, I2C, DDR2/3/4, QDR/QDR-II, InfiniBand, Ethernet, USB, etc.
  • Experience in system-on-chip design concepts
  • Experience with register-based interface control on PCIe boards and high throughput DMA transfer mechanisms.
  • Experience in genetic sequencing or biotechnology instrument development is a big plus but not essential

 

Responsibilities

  • Supporting the development of Depixus’ innovative SIMDEQ instrument platform for combined genetic and epigenetic analysis.
  • Specifically:
    • Define and implement FPGA and ASIC designs for genetic analysis via requirement gathering, architecture design, design implementation and verification
    • Write robust, maintainable and documented RTL designs using the best engineering practice
    • Work closely with other engineering groups, including electronic engineering, IC design, software engineering and mechanical engineering, for product development and integration.
  • Contribution to internal and external, informal and formal design reviews
  • Participation in group meetings, and presentation of work to group members

 

Location

  • The job will be based primarily in Depixus’ offices/labs in Harston, Cambridge, U.K. but will also involve frequent travel to the company’s offices/labs in Paris,

 

Application procedure

  • Please send a current C.V. and cover letter via email to Depixus’ Chief Technology Officer, Chas Andre, at: chas.andre@depixus.com

Depixus is a young and fast-growing biotechnology company based in both Paris, France and Cambridge, UK. Our aim is to commercialize a highly innovative technology platform for the fast, accurate, and inexpensive extraction of genetic and epigenetic information from single molecules of DNA and RNA. Originally developed in the Physics Department of École Normale Supérieure (ENS) in Paris, the potential of this exciting technology has been recognized through the award of numerous grants and prizes for innovation at both national and international levels. You can read more about Depixus on our website (www.depixus.com).

Depixus currently has an open position for a full-time project coordinator to work on various projects related to the development of our technology platform. This is a rare opportunity to play an important role in the development of a cutting-edge technology, and as part of a dynamic early-stage company.

 

Job Description

We are seeking an exceptional individual who enjoys working in a highly collaborative and fast paced R&D environment. The successful candidate will coordinate with biologists, engineers, physicists and software engineers, both within Depixus and as part of collaborations with academic and OEM partners. They will play an important role in the commercialization of our innovative new technology platform for the identification, sequencing, and epigenetic analysis of DNA and RNA. The successful candidate will be part of Depixus’ administration team and will be based primarily in Harston, Cambridgeshire, UK. They will:

  • Assist the project leads in coordinating a variety of the company’s innovative R&D programs.
  • Coordinate project planning, organisation, preparation and administration of these programs, to ensure they are carried out in compliance with Depixus’ company policies and, where relevant, the requirements of regulatory bodies and/or funding agencies.
  • Provide guidance and support in preparing project reports.
  • Improve the efficiency and quality of project execution in Depixus based on the principles used in Quality Management Systems (QMS).

Overall, this role would suit candidates who are highly motivated to deliver top quality work with particular attention to detail in project execution.

 

Required Qualifications, Experience, and Qualities

  • Bachelor’s degree in project management or business management with a minimum of 1 year’s relevant industry experience.
  • Candidates with degrees in another discipline, such as engineering, science, marketing, finance or information technology will also be considered. In such case, candidates must demonstrate solid experience and success in performing project coordination duties.
  • Demonstrated experience in successfully managing or coordinating multi-year projects that are funded by private investors or public funders.
  • Demonstrated experience in building and monitoring project budgets.
  • Experience in financial and technical reporting on grant projects.
  • Familiarity with Microsoft Project or similar software tools
  • Excellent project coordination skills, with experience of coordinating remote and culturally diverse project teams.
  • Ability to analyse and organise project resources and establish project priorities.
  • Excellent interpersonal and communications skills.
  • Both a team-player and able to work autonomously.

 

Desirable Qualifications & Experience

  • Excellent English writing skills and grant proposal writing experience.
  • Professional project management or coordination qualification, such as PMP, PRINCE2.
  • Skills in constructing and managing databases.
  • Experience in supplier engagement.

 

Responsibilities

  • Supporting the development of Depixus’ innovative SIMDEQ instrument platform for combined genetic and epigenetic analysis.
  • Specifically:
    • Coordination of project-related activities
    • Management of project budgets, expenses and their reporting
    • Assistance with grant application writing and grant management
    • Performance of administrative tasks to improve Depixus’ framework and environment for project activities

 

Location

  • The job will be based primarily in Depixus’ offices/labs in Harston, Cambridge, U.K. but will also involve frequent travel to the company’s offices/labs in Paris,

 

Application procedure

  • Please send a current C.V. and cover letter via email to Depixus’ Chief Technology Officer, Chas Andre, at: chas.andre@depixus.com

Depixus is a young and fast-growing biotechnology company based in both Paris, France and Cambridge, UK. Our aim is to commercialize a highly innovative technology platform for the fast, accurate, and inexpensive extraction of genetic and epigenetic information from single molecules of DNA and RNA. Originally developed in the Physics Department of École Normale Supérieure (ENS) in Paris, the potential of this exciting technology has been recognized through the award of numerous grants and prizes for innovation at both national and international levels. You can read more about Depixus on our website (www.depixus.com).

Depixus currently has an open position for a full-time Senior Mechanical Design Engineer to work on various projects related to the development of our technology platform. This is a rare opportunity to play an important role in the development of a cutting-edge technology, and as part of a dynamic early-stage company.

 

Job Description

We are seeking an exceptional individual who enjoys working in a highly collaborative and fast paced R&D environment to join our multidisciplinary team. The successful candidate will work with biologists, engineers, physicists and software engineers, both within Depixus and as part of collaborations with academic and OEM partners. They will play an important role in the commercialization of our innovative new technology platform for the identification, sequencing, and epigenetic analysis of DNA and RNA.

The successful candidate will be part of Depixus’ engineering team and will be based primarily in Harston, Cambridgeshire, UK. They will be working on several mechanical challenges in our current and future instrument platforms. They will take ownership of the whole mechanical system and its subsystems for our digital genetic analysis platform. These systems include DNA/RNA sample preparation and analysis of biological materials incorporating microfluidics, fluidic handling, biochemistry, thermal sensing and control, electronics, optics and mechanical functional modules. They will be a key contributor to the platform development from requirement gathering, concept generation, design prototyping, design implementation, fabrication, test and integration. They will develop test strategies, perform risk analysis, troubleshoot interdisciplinary electromechanical and fluidics systems, identify root cause and implement corrective actions during the product development.  They will engage in developing the instrument and guiding development process through to volume production under relevant regulatory safety standards and directories. Therefore, familiarity with CE marking, FDA approval process and QMS in medical device is beneficial.

More generally, the successful candidate will contribute to the overall development of the company’s technology platform. This will include the development and test of various mechanical and fluidics modules within the instrument platform. Close engagement with external partners, manufacturers and test houses will be important. Similarly, close collaboration with other Depixus teams will also be critical to ensure a seamless integration of all functional blocks.

Overall, this role would suit candidates that have a solid background in the mechanical and microfluidics engineering, especially in biomedical applications. Previous experience in the development of systems-on-chip for genetic analysis would be of great value.

 

Required Qualifications, Experience, and Qualities

  • BS/MS/PhD in mechanical engineering or biomedical engineering with a minimum of 10 years relevant industry experience
  • Experienced in at least three of the following areas: control systems, system integration, mass flow and thermodynamics, microfluidics systems, injection moulding and/or optical systems
  • Highly competent in generating mechanical design drawings using Solidworks or other similar mechanical design toolboxes
  • Proficient with performing finite element modelling for fluidics systems and thermodynamic systems
  • Experience with the design, fabrication and test of complex and low-cost microfluidic devices using biocompatible materials and injection moulding techniques, in both prototype quantities and full-scale manufacturing
  • Demonstrated experience with experimental design, failure analysis and root cause analysis
  • Demonstrated hands on engineering capability with proven track record of high quality designs that met product requirements on time and on budget
  • Excellent interpersonal and communications skills
  • Both a team-player and able to work autonomously
  • Highly motivated and results-driven

 

Desirable Qualifications & Experience

  • Experience with MEMS fabrication and nanofabrication
  • Experience with interfacing with biochemistry, surface chemistry and electronic engineering teams
  • Knowledge of software programming or electronic engineer design at system level
  • Knowledge and skills in process and product validation of a variety of equipment and processes used to build medical products, particularly ISO 13485 and FDA QSR experience preferred.
  • General familiarity with life sciences is advantageous but not required

 

Responsibilities

  • Supporting the development of Depixus’ innovative SIMDEQ digital instrument platform for combined genetic and epigenetic analysis.
  • Specifically:
    • Lead the mechanical design involved in the instrument platform development
    • Develop and refine the sample preparation process flow
    • Design, build, verify and validate the mechanical and microfluidics devices for the existing platform and platform under development
    • Collaborate with external partners in product design, fabrication and test
    • Engage in the system integration of the platform and its subsystems
  • Contribution to internal and external, informal and formal design reviews
  • Participation in group meetings, and presentation of work to group members

 

Location

  • The job will be based primarily in Depixus’ offices/labs in Harston, Cambridge, U.K. but will also involve frequent travel to the company’s offices/labs in Paris,

 

Application procedure

Please send a current C.V. and cover letter via email to Depixus’ Chief Technology Officer, Chas Andre, at: chas.andre@depixus.com