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Welcome to the New Era of Single-Molecule Analysis

The Analytical Scientist has published an article by our CEO Gordon Hamilton entitled “Welcome to the New Era of Single-Molecule Analysis” which explores new technologies for studying individual biomolecular interactions at unprecedented scale.

He explains how we have witnessed remarkable advances in the scale and resolution of genomics, transcriptomics, and proteomics that have generated powerful new insights into health and disease. But to truly grasp the mechanisms of life, we must look even deeper than today’s mainstream technologies allow – exploring the interactions of individual molecules that drive cellular function and behavior.

Characterizing individual biomolecular interactions in detail is one of the keys to unravelling the complexities of life and developing more effective therapeutics. Today’s advances in magnetic force spectroscopy (MFS) are making large-scale single-molecule analysis a reality and setting the stage for a breakthrough in our understanding of life at the molecular level.

Thanks to a number of technical innovations, the Depixus MAGNA One™ MFS system enables researchers to study thousands of individual interactions in parallel and tease out the complexities of molecular biology.

This shift from ‘many-to-one’ to ‘one-to-many’ isn’t just a technical upgrade — it’s a fundamental leap that could reshape how we understand biology and accelerate drug discovery.

Read the full article here: https://theanalyticalscientist.com/issues/2025/articles/june/welcome-to-the-new-era-of-single-molecule-analysis/