Here we demonstrate how the technology underlying Depixus MAGNA One™ can be used to determine the kinetic and thermodynamic parameters of an interaction at the single-molecule level. We use Depixus’ magnetic force spectroscopy to study the hybridization of short DNA oligonucleotides to single-stranded DNA and determine the kinetic and thermodynamic parameters. Furthermore, we show that … Continue reading Single-molecule kinetic measurements by magnetic force spectroscopy