Find out more about MAGNA One & the world of magnetic force spectroscopy
Recent & upcoming events
From international conferences to virtual seminars, join us at upcoming events to learn more about Depixus, engage with our experts, and find out what our technology can do for you.
| Conference | |
|---|---|
| Description | Depixus has two oral presentations and will exhibit MAGNA One at Booth #515 |
| When? | 30th September - 3rd October 2024 |
| Where? | Boston, USA |
| Keywords | RNA therapeutics, PPIs, molecular glues |
| Conference | |
|---|---|
| Description | Biophysical Society 69th Annual Meeting |
| When? | Feb 15, 2025 |
| Where? | Los Angeles, USA |
| Keywords | Magnetic Force Spectroscopy (MFS) |
We also regularly give talks and seminars at research institutions and companies to introduce Depixus’ MFS technology. If you’re interested in us visiting your organization, then do get in touch →
Request here →
| Brochure | |
|---|---|
| Description | Learn how MFS is shaping the future of biomolecular analysis; understand how MAGNA One can impact your molecular research; & detailed product specifications |
| Keywords | MAGNA One, Magnetic Force Spectroscopy (MFS), specifications |
Videos, webinars, & presentations
| Video | |
|---|---|
| Description | See how MAGNA One can be used to study RNA structures & interactions |
| Keywords | MAGNA One, magnetic force spectroscopy, RNA structures, RNA targeted therapeutics |
| Video | |
|---|---|
| Description | See how MAGNA One can be used to study protein-to-protein interactions and the effect of modulators |
| Keywords | MAGNA One, magnetic force spectroscopy, protein-to-protein interactions, molecular glue, PPI inhibitors |
| Webinar | |
|---|---|
| Description | Biophysical Society Webinar 9th October 2024. See biology as it really happens – launch of a powerful magnetic force spectroscopy system to enable real-time study of the dynamics of individual molecular interactions at massive scale |
| Keywords | #RNATherapeutics #DrugDiscovery #Biotech #interactomics#Depixus |
Request here →
Publications
Explore a selection of relevant peer-reviewed papers and preprints, describing how leading researchers are using MAGNA One – and MFS more generally – to uncover new biological insights.
| Publication | |
|---|---|
| Description | Mechanistic analysis of Riboswitch Ligand interactions provides insights into pharmacological control over gene expression |
| Journal | Nature Communications 2024;15(1):8173 |
| Date | September 2024 |
| Keywords | Magnetic force spectroscopy, PreQ1 riboswitch, RNA-ligand binding |
| Prepublication | |
|---|---|
| Description | NMR structures and magnetic force spectroscopy studies of small molecules binding to models of an RNA CAG repeat expansion |
| Journal | BioArchive prepublication |
| Date | August 2024 |
| Keywords | Magnetic force spectroscopy, repeat expansion, RNA targeted therapeutics, Huntington’s disease, spinocerebellar ataxia |
| Publication | |
|---|---|
| Description | Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA |
| Journal | Communications Biology 2021; 4(1):128 |
| Date | January 2021 |
| Keywords | Magnetic force spectroscopy, magnetic tweezers, base modifications, genetic variation, fragile X |
| Poster | |
|---|---|
| Description | Single molecule real-time analysis of dynamic nucleic acid interactions |
| Poster | Discovery on Target 2023, Boston |
| Date | September 2023 |
| Keywords | Magnetic force spectroscopy, RNA-ligand binding, RNA-protein interactions |
Application notes
Explore a selection of our application notes, showing some of the uses of MFS and MAGNA One.
Request here →
| Application note | |
|---|---|
| Description | RNA-targeted drug discovery: Using Depixus MAGNA One to explore RNA-ligand interactions |
| Date | October 2024 |
| Keywords | MAGNA One, magnetic force spectroscopy, RNA targeted drugs |
Request here →
| Application note | |
|---|---|
| Description | RNA-targeted drug discovery: Using Depixus MAGNA One to analyze riboswitch-ligand interactions |
| Date | October 2024 |
| Keywords | MAGNA One, magnetic force spectroscopy, RNA targeted drugs, PreQ1 riboswitch, riboswitch-ligand interactions |
Request here →
| Application note | |
|---|---|
| Description | Molecular glues: Using Depixus MAGNA One to analyze protein-protein interactions |
| Date | November 2024 |
| Keywords | MAGNA One, magnetic force spectroscopy, protein-protein interactions, molecular glue, binding strength |