Our products
At Depixus, we’re pushing the boundaries of molecular science with groundbreaking tools that reveal how biology works at the molecular level. Our Magnetic Force Spectroscopy (MFS) technology brings real-time, high-resolution analysis of individual biomolecular interactions at massive scale, with the power to transform the landscape of molecular research and drug discovery.
Opening up a world of opportunities
From proteins and peptides to small molecules and nucleic acids, MAGNA One allows you to study a vast array of biomolecules in ways previously impossible.
- Reveal biological variability in stunning detail by repeated analyses of thousands of individual interactions
- Probe the energetics of complex multi-way interactions across a wide range of affinities
- Generate detailed kinetic & thermodynamic data
Peptides
Antibodies
Small molecules
DNA
Proteins
RNA
Opening up a world of opportunities
From proteins and peptides to small molecules and nucleic acids, MAGNA One allows you to study a vast array of biomolecules in ways previously impossible.
- Reveal biological variability in stunning detail by repeated analyses of thousands of individual interactions
- Probe the energetics of complex multi-way interactions across a wide range of affinities
- Generate detailed kinetic & thermodynamic data
Peptides
Antibodies
Small molecules
DNA
Proteins
RNA
Experience what goes on at the heart of MAGNA One
Watch our animation to see how Depixus' Magnetic Force Spectroscopy delivers detailed insights into molecular interactions. This short animation demonstrates how our innovative technology provides scientists with a truly unique look into the workings of life at the molecular scale.
What MAGNA One can do for you
Depixus MAGNA One is a versatile tool with applications across a wide range of applications and industries. Whether you're investigating protein interactions, studying RNA dynamics, or probing the energetics of molecular glue complexes, MFS offers unmatched precision and flexibility.
MAGNA One for
drug discovery
Improve confidence in selecting lead compounds, especially for complex drug types & molecular targets.
Example applications:
- Development of small molecule drugs targeting RNA structures or RBPs application notes →
- Development of PROTACs & molecular glues
- Understanding the role of PTMs on antibody binding
“The technology you have is really tailor made for a very efficient screen, minimizing false positives & avoiding false negatives. This is what it is all about. The accuracy & the resolution you have could be a game changer” Gerhard Muller, CSO, SpiroChem
MAGNA One for
applied research
Magnetic force spectroscopy offers a novel approach to studying biomolecular interactions, one that you may not have considered or even come across before. MAGNA One allows you to measure forces and dynamics with unparalleled precision, opening up new avenues for discovery and enhancing the depth of your research.
“MAGNA will provide a truly unique capability to quantitate base-pair unfolding events, to identify the most appropriate molecular interactions to unlock diagnostic assays” Anastasia Callaghan. Professor of Biochemistry & Molecular Biophysics, University of Portsmouth - UK
MAGNA One for
biophysics research
It’s time to say goodbye to hours of hunting through hundreds of fields of view to find rare molecular events. MAGNA One’s power to study tens of thousands of molecules in parallelcan transform your research efficiency.
In turn, MAGNA One can provide you and your research teams with richer, more comprehensive data, leading to deeper insights and more robust biophysical conclusions.
Take a look at our product brochure, to see whether MAGNA One can help you with your research.
"MAGNA One allows us to work with several thousand molecules. That’s very important to us because we’ve shown that every time we increase the number of molecules we can study by a factor of ten, we learn much more about the scientific questions we’re investigating.” Jean-Francois Allemand, Professor Biophysics, ENS – Paris
The user experience
At Depixus, we believe that advanced technology should be made accessible to all researchers. That’s why we’ve designed MAGNA One to be as user-friendly as it is powerful.
Simplified sample preparation
Get started quickly with our range of easy-to-use kits.
Flexible experimental design
Design your experiments with our intuitive software and let system automation take care of the rest.
Data in dazzling detail
Molecular interactions happen in real-time. Take a look at our publications & app notes to get a flavor of what’s possible.
With just a few simple steps, you can set up your experiment and witness molecular interactions unfold before your eyes.
MAGNA One key specifications
| Numbers of molecules tracked in parallel | >10,000 |
| Maximum molecular displacement & resolution | 500 nm, with 2 nm resolution |
| Force environment | 0.01 pN – 23 pN |
| Data acquisition rate | 30 Hz |
| Automated reagent transfer | Up to 7 reagents |
| Sample temperature & stability | 18-25 °C ± 0.1 °C |
| Cartridge re-use | Up to 5 times |
| Bead compatibility | 1 μm, paramagnetic |
| Flow-cell volume | 15 μL |