Blogs

We’ve been working with Dr Jay Schneekloth, a leading expert in RNA-targeted drug discovery, to use Depixus’ magnetic force spectroscopy (MFS) platform to probe the interactions between the PreQ1 bacterial riboswitch and its natural ligand or a synthetic small molecule. In a paper published in Nature Communications,1 we showed how our magnetic force spectroscopy technology…

Life runs on biomolecular interactions. A complex network of interactions between DNA, RNA, proteins, and other biomolecules underlies all biological processes. Studying these interactions is key to understanding how these processes work in health and disease, and for the development of more effective treatments. New technologies and therapeutic modalities are expanding the drug target universe…

Depixus MAGNA One™ provides a powerful new way to study biomolecular interactions at scale between DNA, RNA, proteins, antibodies, small molecules and more. Based on magnetic force spectroscopy (MFS), Depixus MAGNA One is the first laboratory instrument to deliver direct, real-time measurements of biomolecular interactions across thousands of individual molecules in parallel. What is magnetic…