Using Depixus’ magnetic force spectroscopy platform to explore small molecules targeting RNA riboswitches

We’ve been working with Dr Jay Schneekloth, a leading expert in RNA-targeted drug discovery, to use Depixus’ magnetic force spectroscopy (MFS) platform to probe the interactions between the PreQ1 bacterial riboswitch and its natural ligand or a synthetic small molecule. In a paper published in Nature Communications,1 we showed how our magnetic force spectroscopy technology…

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