Introducing the MAGNA™ Technology

MAGNATM combines multimodal analytical capability with low sample input requirements to detect minute signals associated with native molecules of DNA, RNA and protein.

It will enable life scientists to dive deeper into biology, delivering new insights into health and disease, whilst advancing the development of a new generation of diagnostics and therapeutics.

DNA

DNA

RNA

RNA

Protein

Protein

To reveal their …

Base sequence

With MAGNATM, molecules can be rapidly identified using just a small number of molecular probes. Sequence variability can also be analysed via the same approach

Base sequence
Epigenetic status

Base modification detection with MAGNATM doesn’t require conversion chemistries. A wide range of modifications can be detected and located in a single run with unparalleled levels of precision.

Epigenetic status
Molecular interactions

MAGNATM can also analyse how biomolecules interact with each other. The kinetics of attachment or detachment (kon, koff, and kD) can be measured, providing a powerful new dimension with which to study the genetic world.

Molecular interactions

Watch our animation to find out how MAGNATM works

Animation by Richard Freudenfeld of Freudenfeld Design Ltd, UK

We’re developing kits for rapid preparation of samples for analysis

We’re developing kits for rapid preparation of samples for analysis

Technology_cartridge

Our cartridges contain both analytical reagents and the flow cells where our assays are performed

Technology_benchtop

Data is generated in real-time from a small bench-top instrument

Images: industrial designs of a future MAGNATM One instrument
and its reagent kits and consumables

communication_biology

Read more about our technology …

Detection of genetic variation and base modifications at base-pair resolution on both DNA and RNA

Zhen Wang, Jérôme Maluenda, Laurène Giraut, Thibault Vieille, Andréas Lefevre, David Salthouse, Gaël Radou, Rémi Moulinas, Sandra Astete, Pol D’Avezac, Geoff Smith, Charles André, Jean-François Allemand, David Bensimon, Vincent Croquette,
Jimmy Ouellet & Gordon Hamilton

Communications Biology volume 4, Article number: 128 (2021)
https://www.nature.com/articles/s42003-021-01648-7 – open access